I've received quite a few emails and calls in the last couple of days regarding the new Intranatal Insulin drug therapy that has been mentioned so frequently in the news. You can read about this here http://archneur.ama-assn.org/cgi/content/full/archneurol.2011.233. The data that was reported this week, was initally presented at the 2010 Alzheimer's Association International conference. And, one of the lead researchers, Suzanne Craft, was awarded a research grant from the Alz. Assn. to follow up on these findings. Based on the article above, this will now go into further stages of clinical trials. Please note that only 104 people were used in this particular studay at this time. While it sounds promising, we need to remember that more trials are needed to determine if this is truly effective. Let's hope for the best -- we'll keep our fingers crossed.
Our Walk To End Alzheimer's is coming up in a month. Hard to believe that it is already here. you can still make a contribution if you follow this linkhttp://walktoendalz.kintera.org/faf/donorReg/donorPledge.asp?ievent=454828&lis=1&kntae454828=4D7AE01A5EA5463FA8C3FF9F86D75AE0&supId=48686180 . I would appreciate your support whatever size it is!!
I've been extremely anxious these days and hard to settle myself down. I don't know the reason. I have a lot going on with the walk and some other things, but I just can't seem to get things together in my mind. I know I am a pain to live with -- I'm not liking myself that much these days, let alone know what I'm doing to my husband and others around me.
On a brighter note, it is getting closer and closer to when my son and daughter-in-law move back to the Atlanta area. I'm so glad they are moving back. My son finishes his federal clerkship next week in Washington DC and has taken a law firm job in Atlanta.
The day after our Walk to End Alzheimer's I'm heading to LA and then on to the trip of a lifetime. I am going to Australia. I can't believe it actually. This is something I have wanted to do my entire life and I'm a bit overwhelmed to think that I am actually doing it. It's on my bucket list and I have been trying to tick all those things off. This will be one big thing off that list for sure. Thanks to my son, this is happening. We have looked at going for some time, but there was never a right time. He was always in school or moving or working. But, we have a little window of opportunity before he starts his new job and we've taken it. I couldn't do it without him and I just can't believe that it is finally going to happen. It will have taken 56 years to get there and I'm sure it will be worth the wait!
Friday, September 16, 2011
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4 comments:
Have a great time in Austrialia ... wow what a trip! That would take some 36 hrs from here .... Nice to read your son and daugther in law are returning to Atlanta! Always nice to read your posts! On September 21st it is Alzheimer Day in the Netherlands as well.
I can't imagine what an exciting time you are going to have. Beyond words. Have a ton of fun and don't forget to share some of it with us.
Australia sounds wonderful! Have a great trip!
Have a great time in Australia.
I have both good news and bad news for you in regards to the treatment of Alzheimer's disease. Intranasal insulin stimulates a pathway (Phosphatidylinositol 3/AKT) that if not overstimulated provides some protection against Alzheimer's disease. However, it will likely not work in individuals with presenilin gene mutations (which leads to early onset Alzheimer's disease) or with the APOE4 gene, because these genes inhibit the activation of this pathway. On the other hand, compounds which prevent the formation of peroxynitrites, scavenge peroxynitrites, and partially reverse the damage done by peroxynitrites have consistently proven effective in delaying the onset of Alzheimer's disease, stopping the progression of Alzheimer's disease, and partially reversing Alzheimer's disease in animal models, case studies, and clinical trials of the disease. For instance, Jimbo and colleagues using aromatherapy with essential oils and Akhondzadeh and colleagues using tinctures of essential oils noticed significant improvements in cognitive function in individuals with Alzheimer's disease. I would recommend aromatherapy with essential oils high in phenols such as cinnamon leaf, clove, oregano, thyme, sage, and rosemary. I have treated my mother effectively this way for four years. She recognizes her home again, sleeps through the night, and is much more alert and aware than before she began aromatherapy. Hope this helps you. Once again have a great trip.
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